Introduction of Research

Sensory function represents the initial step through which organisms engage with environmental cues, and it is crucial for eliciting appropriate responses and ensuring survival. We are analyzing the molecular mechanisms underlying thermotaxis and temperature adaptation in fruit flies and the physiological significance, with a specific focus on the functional linkage between thermoreceptors such as TRP channels and the surrounding membrane lipids. Additionally, we aim to uncover the impact of oxidative stress on membrane lipids and receptors, which serves as a key factor contributing to sensory dysfunction observed in aging and diseases. Moreover, we are exploring and developing novel repellents and insecticides targeting sensory mechanisms in insects to create innovative strategies for pest control.

Molecular basis of sensory function and application to insect pest control
A) Sensory molecules are functionally regulated by interactions with surrounding lipids.
B) Development of novel strategies for insect pest control utilizing their sensory functions.