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Introduction of Research
We plan to generate a platform for an integrated understanding of life systems by establishing basic chromosomal engineering technologies such as the production of transchromosomic (Tc) cell/animal models containing several species-derived Mb-sized genomes. Furthermore, we will establish basic technology to produce designed cells and animals by freely introducing the genomes and chromosomes of various organisms into the target cells and animals. Utilizing this technology, we aim to understand the “time” related to all life phenomena and to clarify the designing principle of de novo-living organisms.