Introduction of Research

Living systems are characterized by the dynamic assembly and disassembly of various self-organized biomolecules in response to external environmental changes. Omics-based approaches developed in recent decades have provided a comprehensive understanding of biomolecules as parts of living organisms. However, fundamental questions concerning how these biomolecules are ordered autonomously to form flexible and robust systems remain unanswered. To acquire an integrative understanding of the principles underlying biomolecular organization, we employ multidisciplinary approaches based on detailed analyses of dynamic structures and interactions of biomolecules using molecular and cellular biology techniques accompanied by synthetic and computational techniques.