MEMBERS

Staff

Project Associate Professor: Koji SATO, Ph.D.
E-mail: ksato[at]nips.ac.jp
 

 

Research

The senses of olfaction and gustation are essential chemosensory systems to recognize the tens of thousands of chemical compounds in nature. The genes of olfactory receptors (ORs) encode the large a large family of seven-transmembrane-domain G protein coupled receptors (GPCRs). However insect ORs possess the seven transmembrane topology with the intracellular amino terminus, and comprise the odor-gated ion channels (fig. 1). We focus on the molecular mechanism of signal transduction in chemical senses, which enable the complex neuronal coding of multiple of chemical information.
 

Reference

・Sato, K. (correspondence) and Sorensen, P.W. Chemical Senses, 43:249-260. (2018)
 
・Sato, K. and Takeuchi, S. Angewandte Chemie International Edition, 53:11798-11802. (2014)
(Selected as the Hot Paper and Inside Back Cover of the issue.)
 
・Sato, K., Pellegrino, M., Nakagawa, T., Nakagawa, T., Vosshall, L.B., and Touhara, K. Nature 452:1002-1006. (2008)

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