MEMBERS

Staff

Professor: Koichi KATO, Ph.D.
E-mail: kkato[at]excells.orion.ac.jp
 
Assistant Professor: Maho YAGI-UTSUMI, Ph.D.
E-mail: mahoyagi[at]ims.ac.jp
 

 
Link: Kato Group Website
 
 

Research

Organisms living in extreme environments such as deep-sea trenches develop unique ecological adaptation mechanisms. In addition, even in more familiar environments, some organisms develop peculiar adaptation mechanisms to extreme environmental conditions as exemplified by cryptobiosis. We conduct biomolecular analyses to elucidate the molecular processes underlying these biological adaptation mechanisms. Furthermore, we aim to develop biotechnological applications based on our knowledge of biomolecular systems involved in biological processes adapted to extreme environments. Moreover, we exploit extreme environmental conditions such as microgravity in outer space for controlling biomolecular processes including amyloid formation.

 

Reference

・Yagi-Utsumi, M., Sikdar, A., Kozai, T., Inoue, R., Sugiyama, M., Uchihashi, T., Yagi, H., Satoh, T. and Kato, K. Conversion of functionally undefined homopentameric protein PbaA into a proteasome activator by mutational modification of its C-terminal segment conformation, Protein Eng. Des. Sel. 31, 29-36 (2018)

・http://iss.jaxa.jp/en/kiboexp/news/180719_amyloid.html

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